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Magenta Therapetuics
Cambridge, Massachusetts, United States
30+ days ago
Magenta Therapetuics
Cambridge, Massachusetts, United States
30+ days ago

Description

Are you looking for a role with impact?

Magenta Therapeutics is a clinical-stage biotechnology company developing therapeutics to reset the immune system to cure more patients with devastating and life-threatening diseases. This immune reset approach can be applied through stem cell transplant to multiple diseases, including autoimmune diseases, such as multiple sclerosis and systemic sclerosis; blood cancers, such as acute myeloid leukemia; and genetic diseases, such as sickle cell disease.

Magenta’s comprehensive approach to precision immune system reset will transform many aspects of the transplant process, aiming to make it safer and more effective.  Our culture is fueled by a driven, passionate group of people committed to making a difference, seizing opportunities for maximum impact, and pursuing progress for the patients we seek to serve.

We are seeking a Director/Senior Director to lead the Bioanalytical function at Magenta, setting the overall strategy for the design, analysis, interpretation, transfer and reporting of the bioanalysis of pharmacokinetic data from preclinical and clinical studies in utilizing state-of-the-art methodologies (LC-MS, ELISA. alternative ligand binding assays), working closely with both internal and external parties.  Additional responsibilities include managing direct reports, assisting in preparing and reviewing bioanalytical plans, protocols and reports to meet regulatory requirements and management of bioanalytical activities.

This position offers a unique opportunity to work broadly across Magenta’s pipeline, spanning all development stages and therapeutic indications.  This individual will be a visible contributor to our teams, with responsibilities and input that are both scientific and operational in nature.  Where appropriate, this position will be influential in directing Magenta’s technical capabilities regarding the bioanalytic support of projects.   

You are perfect for this role if you are engaged by and want to be responsible for:

  • Management staff and oversight of bioanalytical assay development, validation and study sample analysis, conducted as appropriate in compliance with GLP regulations and in line with regulatory guidelines
  • Lead the development of BA strategy to meet current analytic needs by managing the implementation of bioanalytical contracts/SOW, plans, and reports to ensure that the BA data meet current/future regulatory and scientific requirements.
  • Work with internal and external subject matter experts and other relevant disciplines to manage and resolve scientific, technical or quality issues and improve study consistency, quality, efficiency and effectiveness.
  • Assist with the coordination of all bioanalysis activities for individual preclinical/clinical programs to ensure alignment of BA data deliverables.
  • Provide oversight for the day-to-day operation of BA work, including the analysis of samples and associated duties, processing of biological samples, ensure adequate levels of reference materials, control matrix, and project-specific consumables and resources, assist in method validation, and data processing/reporting, QC checking and data compilation, and basic operation and routine maintenance of laboratory equipment
  • Instill and adhere to GLP and GCP regulations, relevant SOPs, protocols, policies and safety procedures.

We would be thrilled if you brought the following with you:

  • PhD in Chemistry, Pharmaceutical Sciences, Pharmacokinetics or related discipline with a minimum of 12+ years' relevant industry experience; BA/MS Chemistry, Pharmaceutical Sciences, Pharmacokinetics with a minimum of 15+ years' relevant industry experience
  • Must have good understanding of bioanalytical technology/methods both for small and large molecules and peptides.
  • Must have excellent organization skills and be highly regarded in the in BA/PK area with a strong background with managing external CRO’s.
  • Must have well-grounded experience in drug development concepts – data driven decision making, functioning of project teams/sub-teams, development of protocols, clinical study reports etc.
  • Must have the ability to work in a dynamic team-oriented environment as demonstrated by participating in and contributing to cross functional teams is necessary.

Successful leaders and contributors within Magenta are: 

  • Driven.  You will be focused on the achievement of Magenta’s mission and major corporate goals.
  • Results-focused.  Demonstrated record of exceeding stretch goals, and willing to bring creative problem-solving skills to challenges along the way
  • Intuitive. You will enjoy learning and being involved in the content of our whole business, thriving on a very fast-paced and growing business
  • Collaborative.  You will have demonstrated the ability to achieve objectives across complex projects and organizational structures
  • Process-oriented, yet flexible. You will appreciate and be able to create and drive process, while also recognizing when flexibility is needed.
  • Transparent and Articulate.  You will have the ability to communicate clearly and concisely with all stakeholders
  • Independent. You will be able to self-organize and operate effectively without significant day-to-day oversight, while staying tightly connected to key leaders and teams across the company
  • A role model for the company’s cultural pillars; Courage, Commitment & Excellence

At Magenta, we celebrate our differences. We value the power of a diverse array of folks who bring all of themselves to their work. We embrace cultural, cognitive, social, and professional diversity because we know the only way we’re going to make new cures possible is by working together.



Job Information

  • Job ID: 56500271
  • Location:
    Cambridge, Massachusetts, United States
  • Position Title: Director/Senior Director, Head of Bioanalysis
  • Company Name: Magenta Therapetuics
  • Job Function: Analyst
  • Job Type: Full-Time
Biotechnology

Headquartered in Cambridge, Mass., Magenta Therapeutics (Nasdaq:MGTA) is a clinical-stage biotechnology company developing therapeutics to reset the immune system in order to cure more patients with devastating and life-threatening diseases. This immune reset approach can be applied through stem cell transplant to multiple diseases, including autoimmune diseases, such as multiple sclerosis and systemic sclerosis; blood cancers, such as acute myeloid leukemia; and genetic diseases, such as sickle cell disease. Magenta’s compr...

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