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University of Notre Dame
Notre Dame, IN, United States
26 days ago
University of Notre Dame
Notre Dame, IN, United States
26 days ago


The laboratory of Dr. Mayland Chang in the Department of Chemistry and Biochemistry at the University of Notre Dame seeks a motivated postdoctoral research associate. Projects involve determination of antibacterial properties of small-molecule antibacterials in lead optimization, including against Cloistrodiodes difficile and SARS-CoV-2, as well as other pathogens. The lab uses a multidisciplinary approach to solve challenging biomedical projects, including synthetic organic chemistry, biochemistry, bioanalytical chemistry, proteomics, pharmacology, and animal models of disease. The successful candidate will have the opportunity to work among a large group of scientists of diverse backgrounds and interests within our group.


The candidate should have a Ph.D. in microbiology. The postdoc is expected to work independently to move the research project forward. Responsibilities include: determination of binding and inhibition to putative target(s), antibacterial activity, time-kill assays, checkerboard assay, post antibiotic effect, emergence of resistance, germination and sporulation assays, toxicity in mammalian cells, in vitro SARS-CoV-2 activity, and efficacy evaluation in animal models of infection. Candidates should be highly motivated and detail oriented, should have strong communication skills, ability to work independently and in a team setting in a multidisciplinary environment, ability to work with animals, and excellent organizational skills.

If interested, please send:

  • Cover letter describing how your scientific qualifications and relevant research experience and scientific accomplishments related to the research focus of this project
  • Your CV/resume
  • The names, telephone numbers and e-mail addresses for 2-3 people who can provide a letter of recommendation

Job Information

  • Job ID: 58348013
  • Location:
    Notre Dame, IN, United States
  • Position Title: Postdoctoral Research Associate
  • Company Name: University of Notre Dame
  • Industry: College/University
  • Job Function: Research
  • Job Type: Postdoctoral Fellowship
  • Job Duration: Long-term
  • Min Education: Ph.D.
  • Min Experience: None
  • Required Travel: None
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